Antimicrobial resistance and antibiotic biosynthesis in soils: developing key understanding and counteractive strategies using a One-Health approach

The Horizon Europe call "Antimicrobial Resistance and Antibiotic Biosynthesis in Soil: Key Understanding and Counterstrategies with a One Health Approach" targets transnational consortia composed of educational institutions, companies, public authorities, and non-profit organizations. Interdisciplinary research and innovation projects are funded that investigate the mechanisms of resistance development as well as the natural biosynthetic pathways of antibiotics in soil. A focus lies on identifying influencing factors such as land use and management practices. Building on state-of-the-art methods in environmental, health, and veterinary sciences, databases on antibiotic-relevant genes in soil microorganisms are to be expanded and specific guidelines for policy and land management developed. Results will be provided in the form of practical action guides, and targeted communication measures will strengthen public awareness of the value of soil health. Projects are open for electronic submission until 23 September 2026 and will be supported with a total funding amount of EUR 14 million (funding rate 100%).

Eligible to participate are consortia of at least three legally independent organizations from different EU Member States or Horizon Europe associated countries that comply with ethical requirements and submit data protection and financial plans. Personnel costs, material expenses, and subcontracting services are eligible for funding. Evaluation is based on scientific excellence, expected impact, and efficiency of project implementation. Close cooperation with EU initiatives such as the EU Soil Observatory and the SoilWise project is sought. Inclusion of already funded projects from the European One Health Partnership against Antimicrobial Resistance is encouraged. The results should ensure open access and sustainability as well as support national and international decision-makers in implementing evidence-based measures.